3i1h
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3i1h is ON HOLD Authors: Guan, Rongjin, Xiao, Rong, Zhao, Li, Acton, Thomas, White, Eileen, Gelinas, Celine, Montelione, Gaetano T., Northeast Struc...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human BFL-1 in complex with BAK BH3 peptide== | |
| + | <StructureSection load='3i1h' size='340' side='right'caption='[[3i1h]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3i1h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I1H FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i1h OCA], [https://pdbe.org/3i1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i1h RCSB], [https://www.ebi.ac.uk/pdbsum/3i1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i1h ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/B2LA1_HUMAN B2LA1_HUMAN] Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i1/3i1h_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i1h ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[B-cell lymphoma proteins 3D structures|B-cell lymphoma proteins 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Homo sapiens]] | |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Acton T]] | ||
| + | [[Category: Gelinas C]] | ||
| + | [[Category: Guan R]] | ||
| + | [[Category: Montelione GT]] | ||
| + | [[Category: White E]] | ||
| + | [[Category: Xiao R]] | ||
| + | [[Category: Zhao L]] | ||
Current revision
Crystal structure of human BFL-1 in complex with BAK BH3 peptide
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Categories: Homo sapiens | Large Structures | Acton T | Gelinas C | Guan R | Montelione GT | White E | Xiao R | Zhao L
