3hzn

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{{Seed}}
 
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[[Image:3hzn.jpg|left|200px]]
 
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==Structure of the Salmonella typhimurium nfnB dihydropteridine reductase==
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The line below this paragraph, containing "STRUCTURE_3hzn", creates the "Structure Box" on the page.
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<StructureSection load='3hzn' size='340' side='right'caption='[[3hzn]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3hzn]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HZN FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene>, <scene name='pdbligand=TLA:L(+)-TARTARIC+ACID'>TLA</scene></td></tr>
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{{STRUCTURE_3hzn| PDB=3hzn | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hzn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hzn OCA], [https://pdbe.org/3hzn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hzn RCSB], [https://www.ebi.ac.uk/pdbsum/3hzn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hzn ProSAT], [https://www.topsan.org/Proteins/CSGID/3hzn TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NFSB_SALTY NFSB_SALTY] Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hz/3hzn_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hzn ConSurf].
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<div style="clear:both"></div>
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===Structure of the Salmonella typhimurium nfnB dihydropteridine reductase===
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==See Also==
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*[[Nitroreductase 3D structures|Nitroreductase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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3HZN is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium_str._lt2 Salmonella enterica subsp. enterica serovar typhimurium str. lt2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HZN OCA].
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[[Category: Large Structures]]
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[[Category: Salmonella enterica subsp. enterica serovar typhimurium str. lt2]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Anderson, S M.]]
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[[Category: Anderson SM]]
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[[Category: Anderson, W F.]]
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[[Category: Anderson WF]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Onopriyenko O]]
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[[Category: Onopriyenko, O.]]
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[[Category: Savchenko A]]
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[[Category: Savchenko, A.]]
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[[Category: Skarina T]]
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[[Category: Skarina, T.]]
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[[Category: Wawrzak Z]]
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[[Category: Wawrzak, Z.]]
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[[Category: 3 layer sandwich]]
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[[Category: Alpha and beta protein]]
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[[Category: Center for structural genomics of infectious disease]]
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[[Category: Csgid]]
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[[Category: Flavoprotein]]
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[[Category: Fmn]]
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[[Category: Fmn-dependent nitroreductase like]]
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[[Category: Nad]]
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[[Category: Nadp]]
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[[Category: Oxidoreductase]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 8 12:48:04 2009''
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Current revision

Structure of the Salmonella typhimurium nfnB dihydropteridine reductase

PDB ID 3hzn

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