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1wcw

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(New page: 200px<br /><applet load="1wcw" size="450" color="white" frame="true" align="right" spinBox="true" caption="1wcw, resolution 1.3&Aring;" /> '''Crystal Structure of ...)
Current revision (13:31, 13 March 2024) (edit) (undo)
 
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[[Image:1wcw.gif|left|200px]]<br /><applet load="1wcw" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1wcw, resolution 1.3&Aring;" />
 
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'''Crystal Structure of Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (Wild type, Native, Form-1 crystal)'''<br />
 
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==About this Structure==
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==Crystal Structure of Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (Wild type, Native, Form-1 crystal)==
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1WCW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with GOL as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Uroporphyrinogen-III_synthase Uroporphyrinogen-III synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.75 4.2.1.75] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1WCW OCA].
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<StructureSection load='1wcw' size='340' side='right'caption='[[1wcw]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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[[Category: Single protein]]
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1wcw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WCW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WCW FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wcw OCA], [https://pdbe.org/1wcw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wcw RCSB], [https://www.ebi.ac.uk/pdbsum/1wcw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wcw ProSAT], [https://www.topsan.org/Proteins/RSGI/1wcw TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5SKH2_THET8 Q5SKH2_THET8]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wc/1wcw_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wcw ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Uroporphyrinogen-III synthase]]
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[[Category: Kuramitsu S]]
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[[Category: Kuramitsu, S.]]
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[[Category: Matsuura T]]
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[[Category: Matsuura, T.]]
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[[Category: Mizohata E]]
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[[Category: Mizohata, E.]]
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[[Category: Murayama K]]
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[[Category: Murayama, K.]]
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[[Category: Sakai H]]
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[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
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[[Category: Shirouzu M]]
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[[Category: Sakai, H.]]
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[[Category: Terada T]]
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[[Category: Shirouzu, M.]]
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[[Category: Yokoyama S]]
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[[Category: Terada, T.]]
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[[Category: Yokoyama, S.]]
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[[Category: GOL]]
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[[Category: congenital erythropoietic porphyria]]
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[[Category: porphyrin]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: structural genomics]]
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[[Category: uroporphyrinogen]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sat Nov 24 23:44:40 2007''
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Current revision

Crystal Structure of Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (Wild type, Native, Form-1 crystal)

PDB ID 1wcw

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