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3icw
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3icw is ON HOLD Authors: Horton, J.R., Qian, Z., Jia, D., Lutz, S.A., Cheng, X. Description: Structure of a Circular Permutation on Lipase B from C...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of a Circular Permutation on Lipase B from Candida Antartica with Bound Suicide Inhibitor== | |
| + | <StructureSection load='3icw' size='340' side='right'caption='[[3icw]], [[Resolution|resolution]] 1.69Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3icw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Moesziomyces_antarcticus Moesziomyces antarcticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ICW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ICW FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.69Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MHH:METHYL+HYDROGEN+(R)-HEXYLPHOSPHONATE'>MHH</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3icw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3icw OCA], [https://pdbe.org/3icw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3icw RCSB], [https://www.ebi.ac.uk/pdbsum/3icw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3icw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LIPB_PSEA2 LIPB_PSEA2] Hydrolysis of triglycerides. Is very stereospecific both in hydrolysis and in organic synthesis and has a potentially important application in glucolipid synthesis. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ic/3icw_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3icw ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Lipase 3D Structures|Lipase 3D Structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| + | [[Category: Moesziomyces antarcticus]] | ||
| + | [[Category: Cheng X]] | ||
| + | [[Category: Horton JR]] | ||
| + | [[Category: Jia D]] | ||
| + | [[Category: Lutz SA]] | ||
| + | [[Category: Qian Z]] | ||
Current revision
Structure of a Circular Permutation on Lipase B from Candida Antartica with Bound Suicide Inhibitor
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