3ehr
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:3ehr.jpg|left|200px]] | ||
| - | + | ==Crystal Structure of Human Osteoclast Stimulating Factor== | |
| - | + | <StructureSection load='3ehr' size='340' side='right'caption='[[3ehr]], [[Resolution|resolution]] 1.95Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3ehr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EHR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EHR FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ehr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ehr OCA], [https://pdbe.org/3ehr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ehr RCSB], [https://www.ebi.ac.uk/pdbsum/3ehr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ehr ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/OSTF1_HUMAN OSTF1_HUMAN] Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.<ref>PMID:10092216</ref> | |
| - | + | == Evolutionary Conservation == | |
| - | == | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | == | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eh/3ehr_consurf.spt"</scriptWhenChecked> |
| - | < | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ehr ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Gao | + | [[Category: Large Structures]] |
| - | [[Category: Niu | + | [[Category: Gao Y]] |
| - | [[Category: Teng | + | [[Category: Niu L]] |
| - | [[Category: Tong | + | [[Category: Teng M]] |
| - | [[Category: Zhang | + | [[Category: Tong S]] |
| - | [[Category: Zhou | + | [[Category: Zhang X]] |
| - | [[Category: Zhu | + | [[Category: Zhou H]] |
| - | + | [[Category: Zhu Z]] | |
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Current revision
Crystal Structure of Human Osteoclast Stimulating Factor
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Categories: Homo sapiens | Large Structures | Gao Y | Niu L | Teng M | Tong S | Zhang X | Zhou H | Zhu Z
