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3h16
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:3h16.png|left|200px]] | ||
| - | + | ==Crystal structure of a bacteria TIR domain, PdTIR from Paracoccus denitrificans== | |
| - | + | <StructureSection load='3h16' size='340' side='right'caption='[[3h16]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3h16]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Paracoccus_denitrificans_PD1222 Paracoccus denitrificans PD1222]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H16 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H16 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h16 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h16 OCA], [https://pdbe.org/3h16 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h16 RCSB], [https://www.ebi.ac.uk/pdbsum/3h16 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h16 ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/PDTIR_PARDP PDTIR_PARDP] NAD(+) hydrolase (NADase) that catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide.<ref>PMID:29395922</ref> | |
| - | + | == Evolutionary Conservation == | |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h1/3h16_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | == | + | </jmolCheckbox> |
| - | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h16 ConSurf]. | |
| - | + | <div style="clear:both"></div> | |
| - | == | + | == References == |
| - | < | + | <references/> |
| - | [[ | + | __TOC__ |
| - | [[ | + | </StructureSection> |
| - | [[ | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Paracoccus denitrificans PD1222]] |
| - | [[Category: | + | [[Category: Chan SL]] |
| - | [[Category: | + | [[Category: Low LY]] |
| - | [[Category: | + | [[Category: Pascual J]] |
| - | + | [[Category: Santelli E]] | |
| - | + | ||
Current revision
Crystal structure of a bacteria TIR domain, PdTIR from Paracoccus denitrificans
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