3irc

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(New page: '''Unreleased structure''' The entry 3irc is ON HOLD Authors: Nelson, C.A., Kim, T., Warren, J.T., Chruszcz, M., Minor, W., Fremont, D.H., Center for Structural Genomics of Infectious D...)
Current revision (07:56, 6 September 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 3irc is ON HOLD
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==Crystal structure analysis of dengue-1 envelope protein domain III==
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<StructureSection load='3irc' size='340' side='right'caption='[[3irc]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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Authors: Nelson, C.A., Kim, T., Warren, J.T., Chruszcz, M., Minor, W., Fremont, D.H., Center for Structural Genomics of Infectious Diseases (CSGID)
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3irc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3egp 3egp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IRC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IRC FirstGlance]. <br>
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Description: Crystal structure analysis of dengue-1 envelope protein domain III
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Sep 3 15:23:09 2009''
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3irc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3irc OCA], [https://pdbe.org/3irc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3irc RCSB], [https://www.ebi.ac.uk/pdbsum/3irc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3irc ProSAT], [https://www.topsan.org/Proteins/CSGID/3irc TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9J7C6_9FLAV Q9J7C6_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]
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__TOC__
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</StructureSection>
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[[Category: Dengue virus 1]]
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[[Category: Large Structures]]
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[[Category: Chruszcz M]]
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[[Category: Fremont DH]]
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[[Category: Kim T]]
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[[Category: Minor W]]
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[[Category: Nelson CA]]
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[[Category: Warren JT]]

Current revision

Crystal structure analysis of dengue-1 envelope protein domain III

PDB ID 3irc

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