2zov

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:40, 6 November 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2zov.png|left|200px]]
 
-
<!--
+
==Structure of the periplasmic domain of MotB from Salmonella (crystal form I)==
-
The line below this paragraph, containing "STRUCTURE_2zov", creates the "Structure Box" on the page.
+
<StructureSection load='2zov' size='340' side='right'caption='[[2zov]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2zov]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZOV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZOV FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
{{STRUCTURE_2zov| PDB=2zov | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zov FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zov OCA], [https://pdbe.org/2zov PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zov RCSB], [https://www.ebi.ac.uk/pdbsum/2zov PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zov ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/MOTB_SALTY MOTB_SALTY] MotA and MotB comprise the stator element of the flagellar motor complex. Required for the rotation of the flagellar motor. Might be a linker that fastens the torque-generating machinery to the cell wall (By similarity).
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zo/2zov_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zov ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Torque generation in the Salmonella flagellar motor is coupled to translocation of H(+) ions through the proton-conducting channel of the Mot protein stator complex. The Mot complex is believed to be anchored to the peptidoglycan (PG) layer by the putative peptidoglycan-binding (PGB) domain of MotB. Proton translocation is activated only when the stator is installed into the motor. We report the crystal structure of a C-terminal periplasmic fragment of MotB (MotB(C)) that contains the PGB domain and includes the entire periplasmic region essential for motility. Structural and functional analyses indicate that the PGB domains must dimerize in order to form the proton-conducting channel. Drastic conformational changes in the N-terminal portion of MotB(C) are required both for PG binding and the proton channel activation.
-
===Structure of the periplasmic domain of MotB from Salmonella (crystal form I)===
+
Stator assembly and activation mechanism of the flagellar motor by the periplasmic region of MotB.,Kojima S, Imada K, Sakuma M, Sudo Y, Kojima C, Minamino T, Homma M, Namba K Mol Microbiol. 2009 Aug;73(4):710-8. Epub 2009 Jul 21. PMID:19627504<ref>PMID:19627504</ref>
 +
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 2zov" style="background-color:#fffaf0;"></div>
-
<!--
+
==See Also==
-
The line below this paragraph, {{ABSTRACT_PUBMED_19627504}}, adds the Publication Abstract to the page
+
*[[Chemotaxis protein 3D structures|Chemotaxis protein 3D structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 19627504 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_19627504}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Large Structures]]
-
2ZOV is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZOV OCA].
+
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
-
 
+
[[Category: Homma M]]
-
==Reference==
+
[[Category: Imada K]]
-
<ref group="xtra">PMID:19627504</ref><references group="xtra"/>
+
[[Category: Kojima S]]
-
[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
+
[[Category: Namba K]]
-
[[Category: Homma, M.]]
+
-
[[Category: Imada, K.]]
+
-
[[Category: Kojima, S.]]
+
-
[[Category: Namba, K.]]
+
-
[[Category: 2-layer sandwich]]
+
-
[[Category: Bacterial flagellum]]
+
-
[[Category: Cell projection]]
+
-
[[Category: Chemotaxis]]
+
-
[[Category: Flagellar rotation]]
+
-
[[Category: Inner membrane]]
+
-
[[Category: Membrane]]
+
-
[[Category: Membrane protein]]
+
-
[[Category: Transmembrane]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Sep 3 15:33:18 2009''
+

Current revision

Structure of the periplasmic domain of MotB from Salmonella (crystal form I)

PDB ID 2zov

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2zov"
Personal tools