2jkv

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{{Seed}}
 
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[[Image:2jkv.jpg|left|200px]]
 
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==Structure of human Phosphogluconate Dehydrogenase in complex with NADPH at 2.53A==
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The line below this paragraph, containing "STRUCTURE_2jkv", creates the "Structure Box" on the page.
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<StructureSection load='2jkv' size='340' side='right'caption='[[2jkv]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2jkv]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JKV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JKV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.532&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_2jkv| PDB=2jkv | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jkv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jkv OCA], [https://pdbe.org/2jkv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jkv RCSB], [https://www.ebi.ac.uk/pdbsum/2jkv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jkv ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/6PGD_HUMAN 6PGD_HUMAN] Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jk/2jkv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jkv ConSurf].
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<div style="clear:both"></div>
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===STRUCTURE OF HUMAN PHOSPHOGLUCONATE DEHYDROGENASE IN COMPLEX WITH NADPH AT 2.53A===
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==See Also==
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*[[6-phosphogluconate dehydrogenase 3D structures|6-phosphogluconate dehydrogenase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2JKV is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JKV OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Large Structures]]
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[[Category: Bountra, C.]]
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[[Category: Arrowsmith CH]]
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[[Category: Delft, F Von.]]
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[[Category: Bountra C]]
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[[Category: Edwards, A.]]
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[[Category: Edwards A]]
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[[Category: Guo, K.]]
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[[Category: Guo K]]
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[[Category: Kavanagh, K L.]]
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[[Category: Kavanagh KL]]
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[[Category: Muniz, J R.C.]]
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[[Category: Muniz JRC]]
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[[Category: Murray, J.]]
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[[Category: Murray J]]
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[[Category: Oppermann, U.]]
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[[Category: Oppermann U]]
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[[Category: Picaud, S.]]
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[[Category: Picaud S]]
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[[Category: Pilka, E S.]]
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[[Category: Pilka ES]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt J]]
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[[Category: Dehydrogenase]]
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[[Category: Von Delft F]]
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[[Category: Nadp]]
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[[Category: Nadph]]
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[[Category: Oxidoreductase]]
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[[Category: Pentose shunt]]
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[[Category: Phosphogluconate]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Sep 3 16:05:31 2009''
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Current revision

Structure of human Phosphogluconate Dehydrogenase in complex with NADPH at 2.53A

PDB ID 2jkv

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