3ggz

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{{Seed}}
 
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[[Image:3ggz.jpg|left|200px]]
 
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==Crystal Structure of S.cerevisiae Ist1 N-terminal domain in complex with Did2 MIM motif==
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The line below this paragraph, containing "STRUCTURE_3ggz", creates the "Structure Box" on the page.
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<StructureSection load='3ggz' size='340' side='right'caption='[[3ggz]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ggz]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GGZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GGZ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ggz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ggz OCA], [https://pdbe.org/3ggz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ggz RCSB], [https://www.ebi.ac.uk/pdbsum/3ggz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ggz ProSAT]</span></td></tr>
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{{STRUCTURE_3ggz| PDB=3ggz | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IST1_YEAST IST1_YEAST] Involved in a late step in sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles. The lumenal sequestrated membrane proteins are targeted into the vacuole after fusion of the endosome with the vacuole. Regulates the recruitment of VPS4 to the ESCRT-III complex, probably in conjunction with DID2, and VPS4 catalyzes the disassembly of the ESCRT-III complex.<ref>PMID:18032582</ref> <ref>PMID:18032584</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gg/3ggz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ggz ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of S.cerevisiae Ist1 N-terminal domain in complex with Did2 MIM motif===
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==See Also==
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*[[Increased sodium tolerance protein|Increased sodium tolerance protein]]
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*[[Vacuolar protein sorting-associated protein 3D structures|Vacuolar protein sorting-associated protein 3D structures]]
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== References ==
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The line below this paragraph, {{ABSTRACT_PUBMED_19477918}}, adds the Publication Abstract to the page
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<references/>
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(as it appears on PubMed at http://www.pubmed.gov), where 19477918 is the PubMed ID number.
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__TOC__
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</StructureSection>
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{{ABSTRACT_PUBMED_19477918}}
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[[Category: Large Structures]]
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==About this Structure==
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3GGZ is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GGZ OCA].
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==Reference==
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<ref group="xtra">PMID:19477918</ref><references group="xtra"/>
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Xiao, J.]]
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[[Category: Xiao J]]
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[[Category: Xu, Z.]]
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[[Category: Xu Z]]
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[[Category: Coiled coil]]
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[[Category: Endocytosis]]
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[[Category: Endosome]]
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[[Category: Membrane]]
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[[Category: Novel mim binding mode]]
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[[Category: Phosphoprotein]]
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[[Category: Protein transport]]
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[[Category: Transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 9 09:23:27 2009''
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Current revision

Crystal Structure of S.cerevisiae Ist1 N-terminal domain in complex with Did2 MIM motif

PDB ID 3ggz

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