3ipv

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{{Seed}}
 
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[[Image:3ipv.jpg|left|200px]]
 
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==Crystal structure of Spatholobus parviflorus seed lectin==
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The line below this paragraph, containing "STRUCTURE_3ipv", creates the "Structure Box" on the page.
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<StructureSection load='3ipv' size='340' side='right'caption='[[3ipv]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ipv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Spatholobus_parviflorus Spatholobus parviflorus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IPV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IPV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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{{STRUCTURE_3ipv| PDB=3ipv | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ipv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ipv OCA], [https://pdbe.org/3ipv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ipv RCSB], [https://www.ebi.ac.uk/pdbsum/3ipv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ipv ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LECA_SPAPA LECA_SPAPA]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ip/3ipv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ipv ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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A galactose-specific seed lectin from Spatholobous parviflorus (SPL) has been purified, crystallized and its X-ray structure solved. It is the first lectin purified and crystallized from the genus Spatholobus (family: Fabaceae). The crystals belong to the space group P1, with a=60.792 A, b=60.998 A, c=78.179 A, alpha=78.68 degrees , beta=88.62 degrees , gamma=104.32 degrees . The data were collected at 2.04 A resolution under cryocondition, on a MAR image-plate detector system, mounted on a rotating anode X-ray generator. The coordinates of Dolichos biflorus lectin (1lu1) were successfully used for the structure solution by molecular replacement method. The primary structure of the SPL was not known earlier and it was unambiguously visible in the electron density. S. parviflorus lectin is a hetero-dimeric-tetramer with two alpha and two beta chains of 251 and 239 residues respectively. SPL has two metal ions, Ca(2+) and Mn(2+), bound to a loop region of each chain. The SPL monomers are in jelly roll form.
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===Crystal structure of Spatholobus parviflorus seed lectin===
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X-ray structure of a galactose-specific lectin from Spatholobous parviflorous.,Geethanandan K, Abhilash J, Bharath SR, Sadasivan C, Haridas M Int J Biol Macromol. 2011 Dec 1;49(5):992-8. Epub 2011 Aug 26. PMID:21889532<ref>PMID:21889532</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==About this Structure==
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</div>
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3IPV is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Spatholobus_parviflorus Spatholobus parviflorus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IPV OCA].
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<div class="pdbe-citations 3ipv" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Spatholobus parviflorus]]
[[Category: Spatholobus parviflorus]]
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[[Category: Abhilash, J.]]
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[[Category: Abhilash J]]
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[[Category: Bharath, S R.]]
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[[Category: Bharath SR]]
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[[Category: Geethanandan, K.]]
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[[Category: Geethanandan K]]
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[[Category: Haridas, M.]]
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[[Category: Haridas M]]
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[[Category: Sadasivan, C.]]
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[[Category: Sadasivan C]]
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[[Category: Anti fungal]]
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[[Category: Galactose binding]]
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[[Category: Hemagglutinin]]
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[[Category: Legume lectin]]
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[[Category: Seed lectin]]
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[[Category: Sugar binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 9 09:52:48 2009''
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Current revision

Crystal structure of Spatholobus parviflorus seed lectin

PDB ID 3ipv

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