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3jq5
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3jq5 is ON HOLD Authors: Mirza, Z., Vikram, G., Singh, N., Sinha, M., Bhushan, A., Sharma, S., Srinivasan, A., Kaur, P., Singh, T.P. Description: P...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Phospholipase A2 Prevents the Aggregation of Amyloid Beta Peptides: Crystal Structure of the Complex of Phospholipase A2 with Octapeptide Fragment of Amyloid Beta Peptide, Asp-Ala-Glu-Phe-Arg-His-Asp-Ser at 2 A Resolution== | |
| + | <StructureSection load='3jq5' size='340' side='right'caption='[[3jq5]], [[Resolution|resolution]] 2.03Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3jq5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Naja_sagittifera Naja sagittifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JQ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JQ5 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jq5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jq5 OCA], [https://pdbe.org/3jq5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jq5 RCSB], [https://www.ebi.ac.uk/pdbsum/3jq5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jq5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PA2A3_NAJSG PA2A3_NAJSG] PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jq/3jq5_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jq5 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| - | + | *[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Homo sapiens]] | |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Naja sagittifera]] | ||
| + | [[Category: Bhushan A]] | ||
| + | [[Category: Kaur P]] | ||
| + | [[Category: Mirza Z]] | ||
| + | [[Category: Sharma S]] | ||
| + | [[Category: Singh N]] | ||
| + | [[Category: Singh TP]] | ||
| + | [[Category: Sinha M]] | ||
| + | [[Category: Srinivasan A]] | ||
| + | [[Category: Vikram G]] | ||
Current revision
Phospholipase A2 Prevents the Aggregation of Amyloid Beta Peptides: Crystal Structure of the Complex of Phospholipase A2 with Octapeptide Fragment of Amyloid Beta Peptide, Asp-Ala-Glu-Phe-Arg-His-Asp-Ser at 2 A Resolution
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Categories: Homo sapiens | Large Structures | Naja sagittifera | Bhushan A | Kaur P | Mirza Z | Sharma S | Singh N | Singh TP | Sinha M | Srinivasan A | Vikram G
