User:Amy Kerzmann/Sandbox 1
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== Inhibition of the M2 Channel from Influenza A == | == Inhibition of the M2 Channel from Influenza A == | ||
| - | Overview of Normal Function: | ||
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| - | Influenza A virions bind to host cells via interactions between hemagglutinin and host cell gangliosides (or sialyated proteins), which trigger receptor-mediated endocytosis. As the virion-containing endosomes are acidified during the typical maturation process, hemagglutin undergoes a conformational change that leads to membrane fusion. Simultaneously, the M2 channel is activated by the acidic conditions, permitting the flow of proteins from the endosomal lumen to the inside of the viral envelope. This acidification process enhances the rate of viral uncoating that releases viral RNA and other components into the cytosol of the infected cell. In this manner, the function of the M2 channel is essential for viral infectivity. | ||
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| + | Sarah is creating a new page for this protein. :) | ||
| - | <applet load='2kad' size='300' frame='true' align='right' caption='Insert caption here' /> | ||
| - | + | == New Demo Page == | |
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| - | + | For demo help, I've started a new page for you about the [[User:Amy Kerzmann/Sandbox 3| Voltage-Gated Potassium Channel]]. | |
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Current revision
Inhibition of the M2 Channel from Influenza A
Content removed!
Sarah is creating a new page for this protein. :)
New Demo Page
For demo help, I've started a new page for you about the Voltage-Gated Potassium Channel. .
