3im1

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{{Seed}}
 
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[[Image:3im1.png|left|200px]]
 
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==Structure of the C-terminal Sec63 unit of yeast Brr2, P212121 Form==
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The line below this paragraph, containing "STRUCTURE_3im1", creates the "Structure Box" on the page.
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<StructureSection load='3im1' size='340' side='right'caption='[[3im1]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3im1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IM1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IM1 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3im1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3im1 OCA], [https://pdbe.org/3im1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3im1 RCSB], [https://www.ebi.ac.uk/pdbsum/3im1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3im1 ProSAT]</span></td></tr>
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{{STRUCTURE_3im1| PDB=3im1 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BRR2_YEAST BRR2_YEAST] RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly. Mediates changes in the dynamic network of RNA-RNA interactions in the spliceosome. Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome.<ref>PMID:19098916</ref> <ref>PMID:23124065</ref> <ref>PMID:19716790</ref> <ref>PMID:19525970</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/im/3im1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3im1 ConSurf].
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<div style="clear:both"></div>
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===Structure of the C-terminal Sec63 unit of yeast Brr2, P212121 Form===
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==See Also==
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*[[Helicase 3D structures|Helicase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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3IM1 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IM1 OCA].
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Hrmann, R L.]]
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[[Category: Hrmann RL]]
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[[Category: Pena, V.]]
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[[Category: Pena V]]
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[[Category: Wahl, M C.]]
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[[Category: Wahl MC]]
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[[Category: Atp-binding]]
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[[Category: Atpase]]
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[[Category: Helicase]]
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[[Category: Hydrolase]]
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[[Category: Molecular modeling]]
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[[Category: Mrna processing]]
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[[Category: Mrna splicing]]
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[[Category: Nucleotide-binding]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Pre-mrna splicing]]
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[[Category: Rna helicase]]
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[[Category: Rna unwindase]]
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[[Category: Rnpase]]
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[[Category: Spliceosome]]
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[[Category: Spliceosome catalytic activation]]
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[[Category: U5-200k protein/brr2]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 17:26:01 2009''
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Current revision

Structure of the C-terminal Sec63 unit of yeast Brr2, P212121 Form

PDB ID 3im1

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