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2kmn
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:2kmn.png|left|200px]] | ||
| - | + | ==Solution structure of peptide deformylase complexed with actinonin== | |
| - | + | <StructureSection load='2kmn' size='340' side='right'caption='[[2kmn]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2kmn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KMN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KMN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kmn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kmn OCA], [https://pdbe.org/2kmn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kmn RCSB], [https://www.ebi.ac.uk/pdbsum/2kmn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kmn ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/DEF_ECOLI DEF_ECOLI] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163] | |
| - | + | == Evolutionary Conservation == | |
| - | == | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | == | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/km/2kmn_consurf.spt"</scriptWhenChecked> |
| - | < | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[ | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [ | + | </jmolCheckbox> |
| - | [ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kmn ConSurf]. |
| - | [ | + | <div style="clear:both"></div> |
| - | [ | + | __TOC__ |
| - | [[ | + | </StructureSection> |
| - | [ | + | [[Category: Escherichia coli K-12]] |
| - | [[ | + | [[Category: Large Structures]] |
| - | [ | + | [[Category: Amero CD]] |
| - | [[Category: | + | [[Category: Byerly DW]] |
| - | [[Category: | + | [[Category: Foster MP]] |
| - | [[Category: | + | [[Category: McElroy CA]] |
| - | [[Category: | + | |
| - | [[Category: | + | |
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| - | + | ||
Current revision
Solution structure of peptide deformylase complexed with actinonin
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