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3f2u

From Proteopedia

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{{Seed}}
 
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[[Image:3f2u.png|left|200px]]
 
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==Crystal structure of human chromobox homolog 1 (CBX1)==
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The line below this paragraph, containing "STRUCTURE_3f2u", creates the "Structure Box" on the page.
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<StructureSection load='3f2u' size='340' side='right'caption='[[3f2u]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3f2u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F2U FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f2u OCA], [https://pdbe.org/3f2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f2u RCSB], [https://www.ebi.ac.uk/pdbsum/3f2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f2u ProSAT]</span></td></tr>
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{{STRUCTURE_3f2u| PDB=3f2u | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of human chromobox homolog 1 (CBX1)===
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[https://www.uniprot.org/uniprot/CBX1_HUMAN CBX1_HUMAN] Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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3F2U is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F2U OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f2/3f2u_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3f2u ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Amaya, M F.]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Amaya MF]]
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[[Category: Botchkarev, A.]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C.]]
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[[Category: Botchkarev A]]
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[[Category: Edwards, A M.]]
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[[Category: Bountra C]]
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[[Category: Kozieradzki, I.]]
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[[Category: Edwards AM]]
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[[Category: Loppnau, P.]]
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[[Category: Kozieradzki I]]
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[[Category: Min, J.]]
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[[Category: Loppnau P]]
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[[Category: Ouyang, H.]]
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[[Category: Min J]]
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[[Category: Ravichandran, M.]]
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[[Category: Ouyang H]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Ravichandran M]]
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[[Category: Tempel, W.]]
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[[Category: Tempel W]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt J]]
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[[Category: Wernimont, A K.]]
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[[Category: Wernimont AK]]
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[[Category: Cbx1]]
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[[Category: Centromere]]
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[[Category: Human chromobox homolog 1]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Protein binding]]
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[[Category: Sgc]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics consortium]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 20:14:02 2009''
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Current revision

Crystal structure of human chromobox homolog 1 (CBX1)

PDB ID 3f2u

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