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3g9g

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{{Seed}}
 
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[[Image:3g9g.jpg|left|200px]]
 
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==Crystal Structure of the N-terminal EFC/F-BAR domain of Syp1==
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The line below this paragraph, containing "STRUCTURE_3g9g", creates the "Structure Box" on the page.
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<StructureSection load='3g9g' size='340' side='right'caption='[[3g9g]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3g9g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G9G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G9G FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g9g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g9g OCA], [https://pdbe.org/3g9g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g9g RCSB], [https://www.ebi.ac.uk/pdbsum/3g9g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g9g ProSAT]</span></td></tr>
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{{STRUCTURE_3g9g| PDB=3g9g | SCENE= }}
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</table>
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== Function ==
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===Crystal Structure of the N-terminal EFC/F-BAR domain of Syp1===
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[https://www.uniprot.org/uniprot/SYP1_YEAST SYP1_YEAST] Multi-functional protein that contributes to the endocytic process, but also to events that occur at the neck during budding and/or cytokinesis. Plays a role as an endocytic adapters with membrane-tubulation activity that associates with transmembrane cargo proteins and initiates the formation of endocytic sites. Contributes to the stabilization of the nascent clathrin-coated pit. Plays also a role in late endocytosis by mediating vesiculation. Involved in the regulation of cell cycle-dependent dynamics of the septin cytoskeleton by promoting septin turnover in different cell cycle stages. May act through the RHO2 signaling pathway to repolarize cortical actin patches in profilin-deficient cells.<ref>PMID:11014808</ref> <ref>PMID:18791237</ref> <ref>PMID:19713939</ref> <ref>PMID:19776351</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 19713939 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g9/3g9g_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_19713939}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3g9g ConSurf].
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3G9G is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G9G OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:19713939</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Barker, S.]]
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[[Category: Barker S]]
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[[Category: Hurley, J.]]
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[[Category: Hurley J]]
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[[Category: Im, Y J.]]
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[[Category: Im YJ]]
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[[Category: Maldonado-Baez, L.]]
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[[Category: Maldonado-Baez L]]
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[[Category: Mishra, S.]]
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[[Category: Mishra S]]
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[[Category: Reider, A.]]
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[[Category: Reider A]]
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[[Category: Traub, L.]]
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[[Category: Traub L]]
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[[Category: Wendland, B.]]
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[[Category: Wendland B]]
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[[Category: Adaptor]]
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[[Category: Bar domain]]
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[[Category: Endocytosis]]
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[[Category: Fch]]
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[[Category: Phosphoprotein]]
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[[Category: Syp1]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 23 08:45:54 2009''
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Current revision

Crystal Structure of the N-terminal EFC/F-BAR domain of Syp1

PDB ID 3g9g

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