3iut

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3iut.jpg|left|200px]]
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The entry 3iut is ON HOLD until Paper Publication
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{{STRUCTURE_3iut| PDB=3iut | SCENE= }}
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Authors: Kerr, I.D., Debnath, M., Brinen, L.S.
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===The Crystal Structure of Cruzain in Complex with a Tetrafluorophenoxymethyl Ketone Inhibitor===
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Description: The Crystal Structure of Cruzain in Complex with a Tetrafluorophenoxymethyl Ketone Inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 30 08:59:18 2009''
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The line below this paragraph, {{ABSTRACT_PUBMED_20088534}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 20088534 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20088534}}
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==About this Structure==
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3IUT is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IUT OCA].
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==Reference==
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<ref group="xtra">PMID:20088534</ref><references group="xtra"/>
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[[Category: Cruzipain]]
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[[Category: Trypanosoma cruzi]]
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[[Category: Brinen, L S.]]
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[[Category: Debnath, M.]]
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[[Category: Kerr, I D.]]
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[[Category: Autocatalytic cleavage]]
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[[Category: Disulfide bond]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Mature domain]]
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[[Category: Papain family cysteine protease]]
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[[Category: Protease]]
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[[Category: Thiol protease]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 16:06:32 2010''

Revision as of 14:06, 3 March 2010

Image:3iut.jpg

Template:STRUCTURE 3iut

The Crystal Structure of Cruzain in Complex with a Tetrafluorophenoxymethyl Ketone Inhibitor

Template:ABSTRACT PUBMED 20088534

About this Structure

3IUT is a 1 chain structure with sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.

Reference

  • Brak K, Kerr ID, Barrett KT, Fuchi N, Debnath M, Ang K, Engel JC, McKerrow JH, Doyle PS, Brinen LS, Ellman JA. Nonpeptidic tetrafluorophenoxymethyl ketone cruzain inhibitors as promising new leads for chagas disease chemotherapy. J Med Chem. 2010 Feb 25;53(4):1763-73. PMID:20088534 doi:10.1021/jm901633v

Page seeded by OCA on Wed Mar 3 16:06:32 2010

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