3irc
From Proteopedia
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{{STRUCTURE_3irc| PDB=3irc | SCENE= }} | {{STRUCTURE_3irc| PDB=3irc | SCENE= }} | ||
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===Crystal structure analysis of dengue-1 envelope protein domain III=== | ===Crystal structure analysis of dengue-1 envelope protein domain III=== | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/Q9J7C6_9FLAV Q9J7C6_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3irc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3egp 3egp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IRC OCA]. | |
[[Category: Dengue virus 1]] | [[Category: Dengue virus 1]] | ||
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]] | [[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]] | ||
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[[Category: Virion]] | [[Category: Virion]] | ||
[[Category: Virus]] | [[Category: Virus]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 30 09:09:30 2009'' | ||
Revision as of 09:41, 27 March 2013
Crystal structure analysis of dengue-1 envelope protein domain III
Function
[Q9J7C6_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]
About this Structure
3irc is a 1 chain structure with sequence from Dengue virus 1. This structure supersedes the now removed PDB entry 3egp. Full crystallographic information is available from OCA.
Categories: Dengue virus 1 | CSGID, Center for Structural Genomics of Infectious Diseases. | Chruszcz, M. | Fremont, D H. | Kim, T. | Minor, W. | Nelson, C A. | Warren, J T. | Atp-binding | Center for structural genomics of infectious disease | Csgid | Envelope | Envelope protein | Helicase | Hydrolase | Membrane | Nucleotide-binding | Rna replication | Structural genomic | Transmembrane | Viral protein | Virion | Virus
