3h63

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[[Image:3h63.png|left|200px]]
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{{STRUCTURE_3h63| PDB=3h63 | SCENE= }}
{{STRUCTURE_3h63| PDB=3h63 | SCENE= }}
===Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Mn2+ atoms originally soaked with cantharidin (which is present in the structure in the hydrolyzed form)===
===Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Mn2+ atoms originally soaked with cantharidin (which is present in the structure in the hydrolyzed form)===
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{{ABSTRACT_PUBMED_19601647}}
{{ABSTRACT_PUBMED_19601647}}
==About this Structure==
==About this Structure==
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3H63 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H63 OCA].
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[[3h63]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H63 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:19601647</ref><references group="xtra"/>
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<ref group="xtra">PMID:019601647</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phosphoprotein phosphatase]]
[[Category: Phosphoprotein phosphatase]]
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[[Category: Luchinat, C.]]
[[Category: Luchinat, C.]]
[[Category: Talluri, E.]]
[[Category: Talluri, E.]]
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[[Category: Cytoplasm]]
 
[[Category: Drug design]]
[[Category: Drug design]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
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[[Category: Protein phosphatase]]
[[Category: Protein phosphatase]]
[[Category: Tpr repeat]]
[[Category: Tpr repeat]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 30 09:18:23 2009''
 

Revision as of 15:22, 27 February 2013

Template:STRUCTURE 3h63

Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Mn2+ atoms originally soaked with cantharidin (which is present in the structure in the hydrolyzed form)

Template:ABSTRACT PUBMED 19601647

About this Structure

3h63 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bertini I, Calderone V, Fragai M, Luchinat C, Talluri E. Structural basis of serine/threonine phosphatase inhibition by the archetypal small molecules cantharidin and norcantharidin. J Med Chem. 2009 Aug 13;52(15):4838-43. PMID:19601647 doi:10.1021/jm900610k

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