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3gis
From Proteopedia
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{{STRUCTURE_3gis| PDB=3gis | SCENE= }} | {{STRUCTURE_3gis| PDB=3gis | SCENE= }} | ||
===Crystal Structure of Na-free Thrombin in Complex with Thrombomodulin=== | ===Crystal Structure of Na-free Thrombin in Complex with Thrombomodulin=== | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3gis]] is a 9 chain structure of [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GIS OCA]. | |
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| + | ==See Also== | ||
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019656282</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
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[[Category: Blood clotting]] | [[Category: Blood clotting]] | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
| - | [[Category: Calcium]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Coagulation]] | [[Category: Coagulation]] | ||
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[[Category: Kringle]] | [[Category: Kringle]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
| - | [[Category: Pharmaceutical]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Protein-protein complex]] | [[Category: Protein-protein complex]] | ||
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[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 13:29:01 2009'' | ||
Revision as of 22:02, 26 July 2012
Contents |
Crystal Structure of Na-free Thrombin in Complex with Thrombomodulin
Template:ABSTRACT PUBMED 19656282
About this Structure
3gis is a 9 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Adams TE, Li W, Huntington JA. Molecular basis of thrombomodulin activation of slow thrombin. J Thromb Haemost. 2009 Oct;7(10):1688-95. Epub 2009 Jul 28. PMID:19656282 doi:10.1111/j.1538-7836.2009.03563.x
Categories: Homo sapiens | Thrombin | Adams, T E. | Huntington, J A. | Acute phase | Blood clotting | Blood coagulation | Cleavage on pair of basic residue | Coagulation | Disease mutation | Disulfide bond | Egf-like domain | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Hydroxylation | Kringle | Membrane | Protease | Protein-protein complex | Receptor | Secreted | Serine protease | Thrombophilia | Transmembrane | Zymogen
