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3jz2

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3jz2.jpg|left|200px]]
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The entry 3jz2 is ON HOLD until Paper Publication
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{{STRUCTURE_3jz2| PDB=3jz2 | SCENE= }}
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Authors: Niu, W., Chen, Z., Bush-Pelc, L.A., Bah, A., Gandhi, P.S., Di Cera, E.
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===Crystal structure of human thrombin mutant N143P in E* form===
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Description: Crystal structure of human thrombin mutant N143P in E* form
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 13:44:20 2009''
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==Disease==
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Known disease associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]]
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==About this Structure==
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3JZ2 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JZ2 OCA].
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==Reference==
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<ref group="xtra">PMID:18250335</ref><ref group="xtra">PMID:15152000</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Thrombin]]
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[[Category: Bah, A.]]
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[[Category: Bush-Pelc, L A.]]
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[[Category: Cera, E Di.]]
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[[Category: Chen, Z.]]
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[[Category: Gandhi, P S.]]
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[[Category: Niu, W.]]
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[[Category: Acute phase]]
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[[Category: Blood coagulation]]
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[[Category: Calcium]]
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[[Category: Cleavage on pair of basic residue]]
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[[Category: Disease mutation]]
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[[Category: Disulfide bond]]
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[[Category: Gamma-carboxyglutamic acid]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Kringle]]
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[[Category: Pharmaceutical]]
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[[Category: Polymorphism]]
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[[Category: Protease]]
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[[Category: Secreted]]
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[[Category: Serine protease]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 21 10:42:36 2009''

Revision as of 08:42, 21 October 2009

Image:3jz2.jpg

Template:STRUCTURE 3jz2

Contents

Crystal structure of human thrombin mutant N143P in E* form

Disease

Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this Structure

3JZ2 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Gandhi PS, Chen Z, Mathews FS, Di Cera E. Structural identification of the pathway of long-range communication in an allosteric enzyme. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1832-7. Epub 2008 Feb 4. PMID:18250335
  • Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E. Molecular dissection of Na+ binding to thrombin. J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:15152000 doi:http://dx.doi.org/10.1074/jbc.M401756200

Page seeded by OCA on Wed Oct 21 10:42:36 2009

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