2zvt

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==About this Structure==
==About this Structure==
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2ZVT is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZVT OCA].
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2ZVT is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZVT OCA].
==Reference==
==Reference==
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[[Category: Zinc-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 13:53:39 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 14:23:20 2010''

Revision as of 12:23, 28 January 2010

Image:2zvt.png

Template:STRUCTURE 2zvt

Contents

Cys285Ser mutant PPARgamma ligand-binding domain complexed with 15-deoxy-delta12,14-prostaglandin J2

Template:ABSTRACT PUBMED 19101554

Disease

Known disease associated with this structure: Carotid intimal medial thickness 1 OMIM:[601487], Insulin resistance, severe, digenic OMIM:[601487], Lipodystrophy, familial partial, type 3 OMIM:[601487], Obesity, severe OMIM:[601487], Obesity, resistance to OMIM:[601487], Diabetes, type 2 OMIM:[601487], Glioblastoma, susceptibility to OMIM:[601487]

About this Structure

2ZVT is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Waku T, Shiraki T, Oyama T, Morikawa K. Atomic structure of mutant PPARgamma LBD complexed with 15d-PGJ2: novel modulation mechanism of PPARgamma/RXRalpha function by covalently bound ligands. FEBS Lett. 2009 Jan 22;583(2):320-4. Epub 2008 Dec 26. PMID:19101554 doi:10.1016/j.febslet.2008.12.017

Page seeded by OCA on Thu Jan 28 14:23:20 2010

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