3imx

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Revision as of 07:55, 14 October 2009

Image:3imx.png

Template:STRUCTURE 3imx

Crystal Structure of human glucokinase in complex with a synthetic activator

Template:ABSTRACT PUBMED 19746978

About this Structure

3IMX is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bebernitz GR, Beaulieu V, Dale BA, Deacon R, Duttaroy A, Gao J, Grondine MS, Gupta RC, Kakmak M, Kavana M, Kirman LC, Liang J, Maniara WM, Munshi S, Nadkarni SS, Schuster HF, Stams T, St Denny I, Taslimi PM, Vash B, Caplan SL. Investigation of functionally liver selective glucokinase activators for the treatment of type 2 diabetes. J Med Chem. 2009 Oct 8;52(19):6142-52. PMID:19746978 doi:10.1021/jm900839k

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