3imc
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
- | 3IMC is a 2 chains structure | + | 3IMC is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMC OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Pantothenate biosynthesis]] | [[Category: Pantothenate biosynthesis]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 15:07:39 2010'' |
Revision as of 13:07, 28 January 2010
Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.6 Ang resolution in complex with fragment compound 5-methoxyindole, sulfate and glycerol
About this Structure
3IMC is a 2 chains structure with sequences from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Hung AW, Silvestre HL, Wen S, Ciulli A, Blundell TL, Abell C. Application of fragment growing and fragment linking to the discovery of inhibitors of Mycobacterium tuberculosis pantothenate synthetase. Angew Chem Int Ed Engl. 2009;48(45):8452-6. PMID:19780086 doi:10.1002/anie.200903821
Page seeded by OCA on Thu Jan 28 15:07:39 2010
Categories: Mycobacterium tuberculosis | Pantoate--beta-alanine ligase | Abell, C. | Blundell, T L. | Ciulli, A. | Hung, A W. | Silvestre, H L. | Wen, S. | Atp-binding | Cytoplasm | Drug design | Enzyme | Fragment-based | Ligase | Magnesium | Metal-binding | Nucleotide-binding | Pantothenate biosynthesis