3i5u
From Proteopedia
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===Crystal structure of an O-methyltransferase (NcsB1) from neocarzinostatin biosynthesis in complex with S-adenosylmethionine (SAM) and 2-hydroxy-5-methyl naphthoic acid (MNA)=== | ===Crystal structure of an O-methyltransferase (NcsB1) from neocarzinostatin biosynthesis in complex with S-adenosylmethionine (SAM) and 2-hydroxy-5-methyl naphthoic acid (MNA)=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3i5u]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_carzinostaticus_subsp._neocarzinostaticus Streptomyces carzinostaticus subsp. neocarzinostaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I5U OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019702337</ref><references group="xtra"/> |
[[Category: Streptomyces carzinostaticus subsp. neocarzinostaticus]] | [[Category: Streptomyces carzinostaticus subsp. neocarzinostaticus]] | ||
[[Category: Bruner, S D.]] | [[Category: Bruner, S D.]] | ||
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[[Category: Rossmann-like fold]] | [[Category: Rossmann-like fold]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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Revision as of 10:47, 13 March 2013
Crystal structure of an O-methyltransferase (NcsB1) from neocarzinostatin biosynthesis in complex with S-adenosylmethionine (SAM) and 2-hydroxy-5-methyl naphthoic acid (MNA)
Template:ABSTRACT PUBMED 19702337
About this Structure
3i5u is a 2 chain structure with sequence from Streptomyces carzinostaticus subsp. neocarzinostaticus. Full crystallographic information is available from OCA.
Reference
- Cooke HA, Guenther EL, Luo Y, Shen B, Bruner SD. Molecular basis of substrate promiscuity for the SAM-dependent O-methyltransferase NcsB1, involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin. Biochemistry. 2009 Aug 25. PMID:19702337 doi:10.1021/bi901257q
