3gxu

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===Crystal structure of Eph receptor and ephrin complex===
===Crystal structure of Eph receptor and ephrin complex===
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{{ABSTRACT_PUBMED_19875447}}
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:18708347</ref><ref group="xtra">PMID:11780069</ref><references group="xtra"/>
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<ref group="xtra">PMID:19875447</ref><ref group="xtra">PMID:18708347</ref><ref group="xtra">PMID:11780069</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 28 13:52:54 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 11 22:54:02 2009''

Revision as of 20:54, 11 November 2009

Image:3gxu.png

Template:STRUCTURE 3gxu

Crystal structure of Eph receptor and ephrin complex

Template:ABSTRACT PUBMED 19875447

About this Structure

3GXU is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Qin H, Noberini R, Huan X, Shi J, Pasquale EB, Song J. Structural characterization of the EphA4-Ephrin-B2 complex reveals new features enabling Eph-ephrin binding promiscuity. J Biol Chem. 2010 Jan 1;285(1):644-54. Epub 2009 Oct 29. PMID:19875447 doi:10.1074/jbc.M109.064824
  • Qin H, Shi J, Noberini R, Pasquale EB, Song J. Crystal structure and NMR binding reveal that two small molecule antagonists target the high affinity ephrin-binding channel of the EphA4 receptor. J Biol Chem. 2008 Oct 24;283(43):29473-84. Epub 2008 Aug 14. PMID:18708347 doi:10.1074/jbc.M804114200
  • Himanen JP, Rajashankar KR, Lackmann M, Cowan CA, Henkemeyer M, Nikolov DB. Crystal structure of an Eph receptor-ephrin complex. Nature. 2001 Dec 20-27;414(6866):933-8. PMID:11780069 doi:10.1038/414933a

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