1xxr
From Proteopedia
(New page: 200px<br /><applet load="1xxr" size="450" color="white" frame="true" align="right" spinBox="true" caption="1xxr, resolution 2.00Å" /> '''Structure of a manno...) |
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| - | [[Image:1xxr.gif|left|200px]]<br /><applet load="1xxr" size=" | + | [[Image:1xxr.gif|left|200px]]<br /><applet load="1xxr" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1xxr, resolution 2.00Å" /> | caption="1xxr, resolution 2.00Å" /> | ||
'''Structure of a mannose-specific jacalin-related lectin from Morus Nigra in complex with mannose'''<br /> | '''Structure of a mannose-specific jacalin-related lectin from Morus Nigra in complex with mannose'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The structures of MornigaM and the MornigaM-mannose complex have been | + | The structures of MornigaM and the MornigaM-mannose complex have been determined at 1.8 A and 2.0 A resolution, respectively. Both structures adopt the typical beta-prism motif found in other jacalin-related lectins and their tetrameric assembly closely resembles that of jacalin. The carbohydrate-binding cavity of MornigaM readily binds mannose. No major structural rearrangements can be observed in MornigaM upon binding of mannose. These results allow corroboration of the structure-function relationships within the small group of Moraceae lectins. |
==About this Structure== | ==About this Structure== | ||
| - | 1XXR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Morus_nigra Morus nigra] with MAN, SO4, ACY and GOL as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http:// | + | 1XXR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Morus_nigra Morus nigra] with <scene name='pdbligand=MAN:'>MAN</scene>, <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=ACY:'>ACY</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XXR OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Barre, A.]] | [[Category: Barre, A.]] | ||
| - | [[Category: Damme, E | + | [[Category: Damme, E J.M Van.]] |
| - | [[Category: Peumans, W | + | [[Category: Peumans, W J.]] |
[[Category: Rabijns, A.]] | [[Category: Rabijns, A.]] | ||
| - | [[Category: Ranter, C | + | [[Category: Ranter, C J.De.]] |
[[Category: Rouge, P.]] | [[Category: Rouge, P.]] | ||
[[Category: ACY]] | [[Category: ACY]] | ||
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[[Category: tetrameric b-prism fold]] | [[Category: tetrameric b-prism fold]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:59:45 2008'' |
Revision as of 13:59, 21 February 2008
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Structure of a mannose-specific jacalin-related lectin from Morus Nigra in complex with mannose
Overview
The structures of MornigaM and the MornigaM-mannose complex have been determined at 1.8 A and 2.0 A resolution, respectively. Both structures adopt the typical beta-prism motif found in other jacalin-related lectins and their tetrameric assembly closely resembles that of jacalin. The carbohydrate-binding cavity of MornigaM readily binds mannose. No major structural rearrangements can be observed in MornigaM upon binding of mannose. These results allow corroboration of the structure-function relationships within the small group of Moraceae lectins.
About this Structure
1XXR is a Single protein structure of sequence from Morus nigra with , , and as ligands. Full crystallographic information is available from OCA.
Reference
Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose., Rabijns A, Barre A, Van Damme EJ, Peumans WJ, De Ranter CJ, Rouge P, FEBS J. 2005 Jul;272(14):3725-32. PMID:16008570
Page seeded by OCA on Thu Feb 21 15:59:45 2008
Categories: Morus nigra | Single protein | Barre, A. | Damme, E J.M Van. | Peumans, W J. | Rabijns, A. | Ranter, C J.De. | Rouge, P. | ACY | GOL | MAN | SO4 | Tetrameric b-prism fold
