3ii5
From Proteopedia
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{{STRUCTURE_3ii5| PDB=3ii5 | SCENE= }} | {{STRUCTURE_3ii5| PDB=3ii5 | SCENE= }} | ||
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===The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor=== | ===The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor=== | ||
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{{ABSTRACT_PUBMED_19864136}} | {{ABSTRACT_PUBMED_19864136}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3ii5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3II5 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019864136</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Torres, N.]] | [[Category: Torres, N.]] | ||
[[Category: Xu, W.]] | [[Category: Xu, W.]] | ||
| - | [[Category: Acetylation]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: B-raf]] | [[Category: B-raf]] | ||
[[Category: Cardiomyopathy]] | [[Category: Cardiomyopathy]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
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[[Category: Phorbol-ester binding]] | [[Category: Phorbol-ester binding]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protein-inhibitor complex]] | [[Category: Protein-inhibitor complex]] | ||
[[Category: Proto-oncogene]] | [[Category: Proto-oncogene]] | ||
[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
| - | [[Category: Zinc]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 17:20:31 2009'' | ||
Revision as of 11:01, 13 March 2013
The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor
Template:ABSTRACT PUBMED 19864136
About this Structure
3ii5 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Berger DM, Torres N, Dutia M, Powell D, Ciszewski G, Gopalsamy A, Levin JI, Kim KH, Xu W, Wilhelm J, Hu Y, Collins K, Feldberg L, Kim S, Frommer E, Wojciechowicz D, Mallon R. Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6519-23. Epub 2009 Oct 26. PMID:19864136 doi:10.1016/j.bmcl.2009.10.049
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Breger, D. | Ciszewski, G. | Dutia, M. | Powell, D. | Torres, N. | Xu, W. | Atp-binding | B-raf | Cardiomyopathy | Disease mutation | Kinase | Metal-binding | Nucleotide-binding | Phorbol-ester binding | Phosphoprotein | Protein-inhibitor complex | Proto-oncogene | Serine/threonine-protein kinase | Transferase | Zinc-finger
