3jrl

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3jrl.jpg|left|200px]]
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The entry 3jrl is ON HOLD until Paper Publication
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{{STRUCTURE_3jrl| PDB=3jrl | SCENE= }}
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Authors: Zhang,X., He,Y.T., Liu, S., Yu, Z.H., Wu, L., Zhang, Z.Y.
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===Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor===
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Description: Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 18 18:48:28 2009''
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(as it appears on PubMed at http://www.pubmed.gov), where 20170098 is the PubMed ID number.
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{{ABSTRACT_PUBMED_20170098}}
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==About this Structure==
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3JRL is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JRL OCA].
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==Reference==
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<ref group="xtra">PMID:20170098</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: He,Y T.]]
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[[Category: Liu, S.]]
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[[Category: Wu, L.]]
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[[Category: Yu, Z H.]]
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[[Category: Zhang, Z Y.]]
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[[Category: Zhang,X.]]
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[[Category: Binding affinity]]
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[[Category: Binding selectivity]]
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[[Category: Crystal]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor]]
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[[Category: Receptor]]
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[[Category: Shp2-iib-08 complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 16:47:04 2010''

Revision as of 14:47, 3 March 2010

Image:3jrl.jpg

Template:STRUCTURE 3jrl

Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor

Template:ABSTRACT PUBMED 20170098

About this Structure

3JRL is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Zhang X, He Y, Liu S, Yu Z, Jiang ZX, Yang Z, Dong Y, Nabinger SC, Wu L, Gunawan AM, Wang L, Chan RJ, Zhang ZY. Salicylic Acid Based Small Molecule Inhibitor for the Oncogenic Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (SHP2). J Med Chem. 2010 Feb 19. PMID:20170098 doi:10.1021/jm901645u

Page seeded by OCA on Wed Mar 3 16:47:04 2010

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