This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3k10
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
| - | [[Image:3k10.png|left|200px]] | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3k10", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3k10| PDB=3k10 | SCENE= }} | {{STRUCTURE_3k10| PDB=3k10 | SCENE= }} | ||
| - | |||
===Crystal structure of telomere capping protein Stn1 from Saccharomyces cerevisiae=== | ===Crystal structure of telomere capping protein Stn1 from Saccharomyces cerevisiae=== | ||
| + | {{ABSTRACT_PUBMED_19884503}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/STN1_YEAST STN1_YEAST]] Has a role in telomere length regulation and telomere end protection. Acts as an inhibitor of telomerase loading through its interaction with CDC13.<ref>PMID:9042864</ref><ref>PMID:11230140</ref> | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3k10]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K10 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019884503</ref><references group="xtra"/><references/> |
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Batey, R T.]] | [[Category: Batey, R T.]] | ||
| Line 35: | Line 22: | ||
[[Category: Telomere capping]] | [[Category: Telomere capping]] | ||
[[Category: Winged helix turn helix]] | [[Category: Winged helix turn helix]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 2 09:10:40 2009'' | ||
Revision as of 09:41, 27 March 2013
Contents |
Crystal structure of telomere capping protein Stn1 from Saccharomyces cerevisiae
Template:ABSTRACT PUBMED 19884503
Function
[STN1_YEAST] Has a role in telomere length regulation and telomere end protection. Acts as an inhibitor of telomerase loading through its interaction with CDC13.[1][2]
About this Structure
3k10 is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
- Gelinas AD, Paschini M, Reyes FE, Heroux A, Batey RT, Lundblad V, Wuttke DS. Telomere capping proteins are structurally related to RPA with an additional telomere-specific domain. Proc Natl Acad Sci U S A. 2009 Nov 17;106(46):19298-303. Epub 2009 Nov 2. PMID:19884503
- ↑ Grandin N, Reed SI, Charbonneau M. Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13. Genes Dev. 1997 Feb 15;11(4):512-27. PMID:9042864
- ↑ Grandin N, Damon C, Charbonneau M. Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13. EMBO J. 2001 Mar 1;20(5):1173-83. PMID:11230140 doi:10.1093/emboj/20.5.1173
