3e4z

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==About this Structure==
==About this Structure==
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3E4Z is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E4Z OCA].
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3E4Z is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E4Z OCA].
==Reference==
==Reference==
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[[Category: Secreted]]
[[Category: Secreted]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 9 14:02:12 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 10 15:53:16 2010''

Revision as of 13:53, 10 February 2010

Template:STRUCTURE 3e4z

Contents

Crystal structure of human insulin degrading enzyme in complex with insulin-like growth factor II

Template:ABSTRACT PUBMED 19896952

Disease

Known disease associated with this structure: Intrauterine and postnatal growth retardation OMIM:[147470]

About this Structure

3E4Z is a 4 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Guo Q, Manolopoulou M, Bian Y, Schilling AB, Tang WJ. Molecular basis for the recognition and cleavages of IGF-II, TGF-alpha, and amylin by human insulin-degrading enzyme. J Mol Biol. 2010 Jan 15;395(2):430-43. Epub 2009 Nov 5. PMID:19896952 doi:10.1016/j.jmb.2009.10.072

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