3g05

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{{Seed}}
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==Crystal structure of N-terminal domain (2-550) of E.coli MnmG==
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[[Image:3g05.png|left|200px]]
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<StructureSection load='3g05' size='340' side='right' caption='[[3g05]], [[Resolution|resolution]] 3.49&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3g05]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_o157:h7_str._edl933 Escherichia coli o157:h7 str. edl933]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G05 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3G05 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ces|3ces]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ECs4683, gidA, mnmG, Z5241 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=155864 Escherichia coli O157:H7 str. EDL933])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3g05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g05 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3g05 RCSB], [http://www.ebi.ac.uk/pdbsum/3g05 PDBsum], [http://www.topsan.org/Proteins/BSGI/3g05 TOPSAN]</span></td></tr>
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g0/3g05_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The MnmE-MnmG complex is involved in tRNA modification. We have determined the crystal structure of Escherichia coli MnmG at 2.4-A resolution, mutated highly conserved residues with putative roles in flavin adenine dinucleotide (FAD) or tRNA binding and MnmE interaction, and analyzed the effects of these mutations in vivo and in vitro. Limited trypsinolysis of MnmG suggests significant conformational changes upon FAD binding.
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Structure-function analysis of Escherichia coli MnmG (GidA), a highly conserved tRNA-modifying enzyme.,Shi R, Villarroya M, Ruiz-Partida R, Li Y, Proteau A, Prado S, Moukadiri I, Benitez-Paez A, Lomas R, Wagner J, Matte A, Velazquez-Campoy A, Armengod ME, Cygler M J Bacteriol. 2009 Dec;191(24):7614-9. Epub 2009 Oct 2. PMID:19801413<ref>PMID:19801413</ref>
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The line below this paragraph, containing "STRUCTURE_3g05", creates the "Structure Box" on the page.
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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or leave the SCENE parameter empty for the default display.
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-->
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{{STRUCTURE_3g05| PDB=3g05 | SCENE= }}
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===Crystal structure of N-terminal domain (2-550) of E.coli MnmG===
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_19801413}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 19801413 is the PubMed ID number.
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</StructureSection>
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[[Category: Escherichia coli o157:h7 str. edl933]]
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{{ABSTRACT_PUBMED_19801413}}
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==About this Structure==
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3G05 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli_o157:h7_edl933 Escherichia coli o157:h7 edl933]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G05 OCA].
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==Reference==
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<ref group="xtra">PMID:19801413</ref><references group="xtra"/>
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[[Category: Escherichia coli o157:h7 edl933]]
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[[Category: BSGI, Montreal-Kingston Bacterial Structural Genomics Initiative.]]
[[Category: BSGI, Montreal-Kingston Bacterial Structural Genomics Initiative.]]
[[Category: Cygler, M.]]
[[Category: Cygler, M.]]
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[[Category: Shi, R.]]
[[Category: Shi, R.]]
[[Category: Bsgi]]
[[Category: Bsgi]]
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[[Category: Cytoplasm]]
 
[[Category: Fad]]
[[Category: Fad]]
[[Category: Flavoprotein]]
[[Category: Flavoprotein]]
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[[Category: Trna processing]]
[[Category: Trna processing]]
[[Category: Trna-modification enzyme]]
[[Category: Trna-modification enzyme]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 9 14:21:50 2009''
 

Revision as of 05:39, 10 October 2014

Crystal structure of N-terminal domain (2-550) of E.coli MnmG

3g05, resolution 3.49Å

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