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3jqd

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==About this Structure==
==About this Structure==
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3JQD is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JQD OCA].
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3JQD is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3bmj 3bmj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JQD OCA].
==Reference==
==Reference==
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[[Category: Trypanosoma brucei]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 20 10:37:25 2010''

Revision as of 08:37, 20 January 2010

Image:3jqd.png

Template:STRUCTURE 3jqd

Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-4-oxo-6-phenyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (DX7)

Template:ABSTRACT PUBMED 19916554

About this Structure

3JQD is a 4 chains structure with sequences from Trypanosoma brucei. This structure supersedes the now removed PDB entry 3bmj. Full crystallographic information is available from OCA.

Reference

  • Tulloch LB, Martini VP, Iulek J, Huggan JK, Lee JH, Gibson CL, Smith TK, Suckling CJ, Hunter WN. Structure-Based Design of Pteridine Reductase Inhibitors Targeting African Sleeping Sickness and the Leishmaniases. J Med Chem. 2009 Nov 16. PMID:19916554 doi:10.1021/jm901059x

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