3jsw

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==About this Structure==
==About this Structure==
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3JSW is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JSW OCA].
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3JSW is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JSW OCA].
==Reference==
==Reference==
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[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Dec 24 07:32:29 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 28 14:31:23 2010''

Revision as of 12:31, 28 January 2010

Image:3jsw.png

Template:STRUCTURE 3jsw

Human PDE9 in complex with selective inhibitor

Template:ABSTRACT PUBMED 19919087

About this Structure

3JSW is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Verhoest PR, Proulx-Lafrance C, Corman M, Chenard L, Helal CJ, Hou X, Kleiman R, Liu S, Marr E, Menniti FS, Schmidt CJ, Vanase-Frawley M, Schmidt AW, Williams RD, Nelson FR, Fonseca KR, Liras S. Identification of a brain penetrant PDE9A inhibitor utilizing prospective design and chemical enablement as a rapid lead optimization strategy. J Med Chem. 2009 Dec 24;52(24):7946-9. PMID:19919087 doi:10.1021/jm9015334

Page seeded by OCA on Thu Jan 28 14:31:23 2010

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