3ksl

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[[Image:3ksl.jpg|left|200px]]
 
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{{STRUCTURE_3ksl| PDB=3ksl | SCENE= }}
{{STRUCTURE_3ksl| PDB=3ksl | SCENE= }}
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===Structure of FPT bound to DATFP-DH-GPP===
===Structure of FPT bound to DATFP-DH-GPP===
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{{ABSTRACT_PUBMED_19954434}}
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==Function==
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[[http://www.uniprot.org/uniprot/FNTB_RAT FNTB_RAT]] Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
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{{ABSTRACT_PUBMED_19954434}}
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==About this Structure==
==About this Structure==
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3KSL is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KSL OCA].
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[[3ksl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KSL OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:19954434</ref><references group="xtra"/>
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<ref group="xtra">PMID:019954434</ref><references group="xtra"/><references/>
[[Category: Protein farnesyltransferase]]
[[Category: Protein farnesyltransferase]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Prenyltransferase]]
[[Category: Prenyltransferase]]
[[Category: Transferase]]
[[Category: Transferase]]
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[[Category: Zinc]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Dec 24 07:36:36 2009''
 

Revision as of 20:11, 4 April 2013

Template:STRUCTURE 3ksl

Contents

Structure of FPT bound to DATFP-DH-GPP

Template:ABSTRACT PUBMED 19954434

Function

[FNTB_RAT] Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.

About this Structure

3ksl is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Hovlid ML, Edelstein RL, Henry O, Ochocki J, DeGraw A, Lenevich S, Talbot T, Young VG, Hruza AW, Lopez-Gallego F, Labello NP, Strickland CL, Schmidt-Dannert C, Distefano MD. Synthesis, properties, and applications of diazotrifluropropanoyl-containing photoactive analogs of farnesyl diphosphate containing modified linkages for enhanced stability. Chem Biol Drug Des. 2010 Jan;75(1):51-67. PMID:19954434 doi:10.1111/j.1747-0285.2009.00914.x

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