3l1b

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3l1b.jpg|left|200px]]
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The entry 3l1b is ON HOLD until Paper Publication
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{{STRUCTURE_3l1b| PDB=3l1b | SCENE= }}
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Authors: Xu, W., Lundquist, J.T.
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===Complex Structure of FXR Ligand-binding domain with a tetrahydroazepinoindole compound===
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Description: Complex Structure of FXR Ligand-binding domain with a tetrahydroazepinoindole compound
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 30 13:48:06 2009''
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{{ABSTRACT_PUBMED_20095622}}
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==About this Structure==
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3L1B is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L1B OCA].
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==Reference==
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<ref group="xtra">PMID:20095622</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Lundquist, J T.]]
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[[Category: Xu, W.]]
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[[Category: Fxr agonist]]
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[[Category: Fxr ligand-binding domain]]
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[[Category: Nuclear receptor]]
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[[Category: Nucleus]]
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[[Category: Receptor]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 16:23:11 2010''

Revision as of 14:23, 3 March 2010

Image:3l1b.jpg

Template:STRUCTURE 3l1b

Complex Structure of FXR Ligand-binding domain with a tetrahydroazepinoindole compound

Template:ABSTRACT PUBMED 20095622

About this Structure

3L1B is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lundquist JT, Harnish DC, Kim CY, Mehlmann JF, Unwalla RJ, Phipps KM, Crawley ML, Commons T, Green DM, Xu W, Hum WT, Eta JE, Feingold I, Patel V, Evans MJ, Lai K, Borges-Marcucci L, Mahaney PE, Wrobel JE. Improvement of physiochemical properties of the tetrahydroazepinoindole series of farnesoid X receptor (FXR) agonists: beneficial modulation of lipids in primates. J Med Chem. 2010 Feb 25;53(4):1774-87. PMID:20095622 doi:10.1021/jm901650u

Page seeded by OCA on Wed Mar 3 16:23:11 2010

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