3dv5

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[[Image:3dv5.png|left|200px]]
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{{STRUCTURE_3dv5| PDB=3dv5 | SCENE= }}
{{STRUCTURE_3dv5| PDB=3dv5 | SCENE= }}
===Crystal structure of human beta-secretase in complex with NVP-BAV544===
===Crystal structure of human beta-secretase in complex with NVP-BAV544===
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{{ABSTRACT_PUBMED_19195887}}
{{ABSTRACT_PUBMED_19195887}}
==About this Structure==
==About this Structure==
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3DV5 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DV5 OCA].
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[[3dv5]] is a 3 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DV5 OCA].
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==See Also==
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*[[Beta secretase|Beta secretase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:19195887</ref><references group="xtra"/>
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<ref group="xtra">PMID:019195887</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
[[Category: Rondeau, J M.]]
[[Category: Rondeau, J M.]]
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[[Category: Alternative splicing]]
 
[[Category: Alzheimer's disease]]
[[Category: Alzheimer's disease]]
[[Category: Aspartic protease]]
[[Category: Aspartic protease]]
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[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 30 14:55:21 2009''
 

Revision as of 08:32, 26 July 2012

Template:STRUCTURE 3dv5

Contents

Crystal structure of human beta-secretase in complex with NVP-BAV544

Template:ABSTRACT PUBMED 19195887

About this Structure

3dv5 is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Machauer R, Laumen K, Veenstra S, Rondeau JM, Tintelnot-Blomley M, Betschart C, Jaton AL, Desrayaud S, Staufenbiel M, Rabe S, Paganetti P, Neumann U. Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1366-70. Epub 2009 Jan 22. PMID:19195887 doi:10.1016/j.bmcl.2009.01.055

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