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3jvk

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[[Image:3jvk.png|left|200px]]
 
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{{STRUCTURE_3jvk| PDB=3jvk | SCENE= }}
{{STRUCTURE_3jvk| PDB=3jvk | SCENE= }}
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===Crystal structure of bromodomain 1 of mouse Brd4 in complex with histone H3-K(ac)14===
===Crystal structure of bromodomain 1 of mouse Brd4 in complex with histone H3-K(ac)14===
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{{ABSTRACT_PUBMED_19828451}}
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==Function==
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[[http://www.uniprot.org/uniprot/BRD4_MOUSE BRD4_MOUSE]] Plays a role in a process governing chromosomal dynamics during mitosis.<ref>PMID:10938129</ref>
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{{ABSTRACT_PUBMED_19828451}}
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==About this Structure==
==About this Structure==
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3JVK is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JVK OCA].
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[[3jvk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JVK OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:19828451</ref><references group="xtra"/>
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<ref group="xtra">PMID:019828451</ref><references group="xtra"/><references/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Blankenfeldt, W.]]
[[Category: Blankenfeldt, W.]]
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[[Category: N-acetyl lysine recognition]]
[[Category: N-acetyl lysine recognition]]
[[Category: Signaling protein]]
[[Category: Signaling protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 6 08:59:33 2010''
 

Revision as of 09:22, 27 March 2013

Template:STRUCTURE 3jvk

Contents

Crystal structure of bromodomain 1 of mouse Brd4 in complex with histone H3-K(ac)14

Template:ABSTRACT PUBMED 19828451

Function

[BRD4_MOUSE] Plays a role in a process governing chromosomal dynamics during mitosis.[1]

About this Structure

3jvk is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Vollmuth F, Blankenfeldt W, Geyer M. Structures of the dual bromodomains of the P-TEFb-activating protein Brd4 at atomic resolution. J Biol Chem. 2009 Dec 25;284(52):36547-56. Epub 2009 Oct 13. PMID:19828451 doi:10.1074/jbc.M109.033712
  1. ↑ Dey A, Ellenberg J, Farina A, Coleman AE, Maruyama T, Sciortino S, Lippincott-Schwartz J, Ozato K. A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition. Mol Cell Biol. 2000 Sep;20(17):6537-49. PMID:10938129

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