3kx1

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3kx1.jpg|left|200px]]
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The entry 3kx1 is ON HOLD until Paper Publication
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{{STRUCTURE_3kx1| PDB=3kx1 | SCENE= }}
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Authors: Fradera, X., Uitdehaag, J.C.M., van Zeeland, M.
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===Cathepsin K in complex with a selective 2-cyano-pyrimidine inhibitor===
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Description: Cathepsin K in complex with a selective 2-cyano-pyrimidine inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 6 09:13:19 2010''
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{{ABSTRACT_PUBMED_20149657}}
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==About this Structure==
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3KX1 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KX1 OCA].
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==Reference==
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<ref group="xtra">PMID:20149657</ref><references group="xtra"/>
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[[Category: Cathepsin K]]
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[[Category: Homo sapiens]]
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[[Category: Fradera, X.]]
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[[Category: Uitdehaag, J C.M.]]
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[[Category: Zeeland, M van.]]
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[[Category: Cathepsin k]]
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[[Category: Covalent reversible inhibitor]]
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[[Category: Disease mutation]]
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[[Category: Disulfide bond]]
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[[Category: Enzyme inhibitor]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Lysosome]]
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[[Category: Protease]]
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[[Category: Thiol protease]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 16:01:39 2010''

Revision as of 14:01, 3 March 2010

Image:3kx1.jpg

Template:STRUCTURE 3kx1

Cathepsin K in complex with a selective 2-cyano-pyrimidine inhibitor

Template:ABSTRACT PUBMED 20149657

About this Structure

3KX1 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Rankovic Z, Cai J, Kerr J, Fradera X, Robinson J, Mistry A, Hamilton E, McGarry G, Andrews F, Caulfield W, Cumming I, Dempster M, Waller J, Scullion P, Martin I, Mitchell A, Long C, Baugh M, Westwood P, Kinghorn E, Bruin J, Hamilton W, Uitdehaag J, van Zeeland M, Potin D, Saniere L, Fouquet A, Chevallier F, Deronzier H, Dorleans C, Nicolai E. Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1524-7. Epub 2010 Jan 25. PMID:20149657 doi:10.1016/j.bmcl.2010.01.100

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