3hl5

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[[Image:3hl5.png|left|200px]]
[[Image:3hl5.png|left|200px]]
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{{STRUCTURE_3hl5| PDB=3hl5 | SCENE= }}
{{STRUCTURE_3hl5| PDB=3hl5 | SCENE= }}
===Crystal structure of XIAP BIR3 with CS3===
===Crystal structure of XIAP BIR3 with CS3===
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{{ABSTRACT_PUBMED_19492850}}
{{ABSTRACT_PUBMED_19492850}}
==About this Structure==
==About this Structure==
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3HL5 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HL5 OCA].
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[[3hl5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HL5 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:19492850</ref><references group="xtra"/>
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<ref group="xtra">PMID:019492850</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hymowitz, S G.]]
[[Category: Hymowitz, S G.]]
[[Category: Apoptosis]]
[[Category: Apoptosis]]
[[Category: Bir]]
[[Category: Bir]]
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[[Category: Cytoplasm]]
 
[[Category: Iap]]
[[Category: Iap]]
[[Category: Ligase]]
[[Category: Ligase]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
 
[[Category: Protease inhibitor]]
[[Category: Protease inhibitor]]
[[Category: Small molecule drug discovery]]
[[Category: Small molecule drug discovery]]
[[Category: Structure-based drug design]]
[[Category: Structure-based drug design]]
[[Category: Thiol protease inhibitor]]
[[Category: Thiol protease inhibitor]]
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[[Category: Ubl conjugation]]
 
[[Category: Ubl conjugation pathway]]
[[Category: Ubl conjugation pathway]]
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[[Category: Zinc]]
 
[[Category: Zinc-finger]]
[[Category: Zinc-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jan 18 08:59:12 2010''
 

Revision as of 14:52, 6 March 2013

Template:STRUCTURE 3hl5

Crystal structure of XIAP BIR3 with CS3

Template:ABSTRACT PUBMED 19492850

About this Structure

3hl5 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Ndubaku C, Varfolomeev E, Wang L, Zobel K, Lau K, Elliott LO, Maurer B, Fedorova AV, Dynek JN, Koehler M, Hymowitz SG, Tsui V, Deshayes K, Fairbrother WJ, Flygare JA, Vucic D. Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists. ACS Chem Biol. 2009 Jul 17;4(7):557-66. PMID:19492850 doi:10.1021/cb900083m

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