3keg

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[[Image:3keg.png|left|200px]]
 
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{{STRUCTURE_3keg| PDB=3keg | SCENE= }}
{{STRUCTURE_3keg| PDB=3keg | SCENE= }}
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===X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED===
===X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED===
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{{ABSTRACT_PUBMED_20057057}}
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==Function==
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[[http://www.uniprot.org/uniprot/AZOR1_PSEAE AZOR1_PSEAE]] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity).
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{{ABSTRACT_PUBMED_20057057}}
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==About this Structure==
==About this Structure==
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3KEG is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEG OCA].
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[[3keg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KEG OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20057057</ref><references group="xtra"/>
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<ref group="xtra">PMID:020057057</ref><references group="xtra"/><references/>
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Abuhammad, A.]]
[[Category: Abuhammad, A.]]
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[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Y131f azoreductase]]
[[Category: Y131f azoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 20 08:44:47 2010''
 

Revision as of 02:04, 4 April 2013

Template:STRUCTURE 3keg

Contents

X-ray Crystallographic Structure of a Y131F mutant of Pseudomonas Aeruginosa Azoreductase in complex with Methyl RED

Template:ABSTRACT PUBMED 20057057

Function

[AZOR1_PSEAE] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity).

About this Structure

3keg is a 2 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.

Reference

  • Wang CJ, Laurieri N, Abuhammad A, Lowe E, Westwood I, Ryan A, Sim E. Role of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazide. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jan 1;66(Pt 1):2-7., Epub 2009 Dec 25. PMID:20057057 doi:10.1107/S1744309109044741

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