1pah
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:1pah.png|left|200px]] | [[Image:1pah.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_1pah", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_1pah| PDB=1pah | SCENE= }} | {{STRUCTURE_1pah| PDB=1pah | SCENE= }} | ||
===HUMAN PHENYLALANINE HYDROXYLASE DIMER, RESIDUES 117-424=== | ===HUMAN PHENYLALANINE HYDROXYLASE DIMER, RESIDUES 117-424=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_9406548}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 9406548 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_9406548}} | {{ABSTRACT_PUBMED_9406548}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1pah]] is a 1 chain structure of [[Phenylalanine hydroxylase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The January 2005 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Phenylalanine Hydroxylase'' by Shuchismita Dutta and David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2005_1 10.2210/rcsb_pdb/mom_2005_1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PAH OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Phenylalanine hydroxylase|Phenylalanine hydroxylase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:009406548</ref><ref group="xtra">PMID:009799096</ref><ref group="xtra">PMID:012126628</ref><ref group="xtra">PMID:014695246</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Phenylalanine 4-monooxygenase]] | [[Category: Phenylalanine 4-monooxygenase]] | ||
| Line 35: | Line 26: | ||
[[Category: Phenylketonuria]] | [[Category: Phenylketonuria]] | ||
[[Category: Pku]] | [[Category: Pku]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 21 08:36:33 2010'' | ||
Revision as of 23:26, 25 July 2012
Contents |
HUMAN PHENYLALANINE HYDROXYLASE DIMER, RESIDUES 117-424
Template:ABSTRACT PUBMED 9406548
About this Structure
1pah is a 1 chain structure of Phenylalanine hydroxylase with sequence from Homo sapiens. The January 2005 RCSB PDB Molecule of the Month feature on Phenylalanine Hydroxylase by Shuchismita Dutta and David S. Goodsell is 10.2210/rcsb_pdb/mom_2005_1. Full crystallographic information is available from OCA.
See Also
Reference
- Erlandsen H, Fusetti F, Martinez A, Hough E, Flatmark T, Stevens RC. Crystal structure of the catalytic domain of human phenylalanine hydroxylase reveals the structural basis for phenylketonuria. Nat Struct Biol. 1997 Dec;4(12):995-1000. PMID:9406548
- Bjorgo E, Knappskog PM, Martinez A, Stevens RC, Flatmark T. Partial characterization and three-dimensional-structural localization of eight mutations in exon 7 of the human phenylalanine hydroxylase gene associated with phenylketonuria. Eur J Biochem. 1998 Oct 1;257(1):1-10. PMID:9799096
- Andersen OA, Flatmark T, Hough E. Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation. J Mol Biol. 2002 Jul 26;320(5):1095-108. PMID:12126628
- Sandelin E. On hydrophobicity and conformational specificity in proteins. Biophys J. 2004 Jan;86(1 Pt 1):23-30. PMID:14695246 doi:10.1016/S0006-3495(04)74080-1
