1owt

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{{Seed}}
 
[[Image:1owt.png|left|200px]]
[[Image:1owt.png|left|200px]]
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{{STRUCTURE_1owt| PDB=1owt | SCENE= }}
{{STRUCTURE_1owt| PDB=1owt | SCENE= }}
===Structure of the Alzheimer's disease amyloid precursor protein copper binding domain===
===Structure of the Alzheimer's disease amyloid precursor protein copper binding domain===
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{{ABSTRACT_PUBMED_12611883}}
{{ABSTRACT_PUBMED_12611883}}
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==Disease==
 
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Known disease associated with this structure: Alzheimer disease-1, APP-related OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=104760 104760]], Amyloidosis, cerebroarterial, Dutch type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=104760 104760]], Amyloidosis, cerebroarterial, Iowa type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=104760 104760]]
 
==About this Structure==
==About this Structure==
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1OWT is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The July 2006 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Amyloid-beta Precursor Protein'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2006_7 10.2210/rcsb_pdb/mom_2006_7]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OWT OCA].
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[[1owt]] is a 1 chain structure of [[Amyloid precursor protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The July 2006 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Amyloid-beta Precursor Protein'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2006_7 10.2210/rcsb_pdb/mom_2006_7]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OWT OCA].
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==See Also==
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*[[Amyloid precursor protein|Amyloid precursor protein]]
==Reference==
==Reference==
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<ref group="xtra">PMID:12611883</ref><references group="xtra"/>
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<ref group="xtra">PMID:012611883</ref><references group="xtra"/>
[[Category: Amyloid-beta Precursor Protein]]
[[Category: Amyloid-beta Precursor Protein]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Apoptosis]]
[[Category: Apoptosis]]
[[Category: Beta-alpha-beta-beta]]
[[Category: Beta-alpha-beta-beta]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 21 09:47:05 2010''
 

Revision as of 21:45, 26 July 2012

Image:1owt.png

Template:STRUCTURE 1owt

Contents

Structure of the Alzheimer's disease amyloid precursor protein copper binding domain

Template:ABSTRACT PUBMED 12611883

About this Structure

1owt is a 1 chain structure of Amyloid precursor protein with sequence from Homo sapiens. The July 2006 RCSB PDB Molecule of the Month feature on Amyloid-beta Precursor Protein by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_7. Full experimental information is available from OCA.

See Also

Reference

  • Barnham KJ, McKinstry WJ, Multhaup G, Galatis D, Morton CJ, Curtain CC, Williamson NA, White AR, Hinds MG, Norton RS, Beyreuther K, Masters CL, Parker MW, Cappai R. Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis. J Biol Chem. 2003 May 9;278(19):17401-7. Epub 2003 Feb 28. PMID:12611883 doi:10.1074/jbc.M300629200

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