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1fkn
From Proteopedia
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{{STRUCTURE_1fkn| PDB=1fkn | SCENE= }} | {{STRUCTURE_1fkn| PDB=1fkn | SCENE= }} | ||
===Structure of Beta-Secretase Complexed with Inhibitor=== | ===Structure of Beta-Secretase Complexed with Inhibitor=== | ||
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{{ABSTRACT_PUBMED_11021803}} | {{ABSTRACT_PUBMED_11021803}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1fkn]] is a 4 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The July 2006 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Amyloid-beta Precursor Protein'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2006_7 10.2210/rcsb_pdb/mom_2006_7]. The July 2009 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''beta-Secretase'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2009_7 10.2210/rcsb_pdb/mom_2009_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FKN OCA]. | |
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| + | ==See Also== | ||
| + | *[[Beta secretase|Beta secretase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:011021803</ref><references group="xtra"/> |
[[Category: Amyloid-beta Precursor Protein]] | [[Category: Amyloid-beta Precursor Protein]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Base]] | [[Category: Base]] | ||
[[Category: Beta-secretase]] | [[Category: Beta-secretase]] | ||
| - | [[Category: Hydrolase | + | [[Category: Hydrolase-hydrolase inhibitor complex]] |
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 21 09:57:25 2010'' | ||
Revision as of 12:24, 27 July 2012
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| 1fkn, resolution 1.90Å () | |||||||||
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| Non-Standard Residues: | |||||||||
| Activity: | Memapsin 2, with EC number 3.4.23.46 | ||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
Structure of Beta-Secretase Complexed with Inhibitor
Template:ABSTRACT PUBMED 11021803
About this Structure
1fkn is a 4 chain structure of Beta secretase with sequence from Homo sapiens. The July 2006 RCSB PDB Molecule of the Month feature on Amyloid-beta Precursor Protein by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_7. The July 2009 RCSB PDB Molecule of the Month feature on beta-Secretase by David Goodsell is 10.2210/rcsb_pdb/mom_2009_7. Full crystallographic information is available from OCA.
See Also
Reference
- Hong L, Koelsch G, Lin X, Wu S, Terzyan S, Ghosh AK, Zhang XC, Tang J. Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor. Science. 2000 Oct 6;290(5489):150-3. PMID:11021803
Categories: Amyloid-beta Precursor Protein | Homo sapiens | Memapsin 2 | RCSB PDB Molecule of the Month | Beta-Secretase | Ghosh, A. | Hong, L. | Koelsch, G. | Lin, X. | Tang, J. | Terzyan, S. | Wu, S. | Zhang, X C. | Alzheimer's disease | Aspartic protease | Base | Beta-secretase | Hydrolase-hydrolase inhibitor complex
