1hxb

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{{STRUCTURE_1hxb| PDB=1hxb | SCENE= }}
{{STRUCTURE_1hxb| PDB=1hxb | SCENE= }}
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===HIV-1 PROTEINASE COMPLEXED WITH RO 31-8959===
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===HIV-1 proteinase complexed with RO 31-8959===
==About this Structure==
==About this Structure==
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1HXB is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. The June 2000 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''HIV-1 Protease'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2000_6 10.2210/rcsb_pdb/mom_2000_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXB OCA].
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[[1hxb]] is a 2 chain structure of [[Virus protease]] with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. The June 2000 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''HIV-1 Protease'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2000_6 10.2210/rcsb_pdb/mom_2000_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXB OCA].
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==See Also==
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*[[Virus protease|Virus protease]]
==Reference==
==Reference==
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<ref group="xtra">PMID:1956054</ref><references group="xtra"/>
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<ref group="xtra">PMID:001956054</ref><ref group="xtra">PMID:002183354</ref><ref group="xtra">PMID:011106162</ref><references group="xtra"/>
[[Category: HIV-1 Protease]]
[[Category: HIV-1 Protease]]
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
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[[Category: Graves, B J.]]
[[Category: Graves, B J.]]
[[Category: Hatada, M H.]]
[[Category: Hatada, M H.]]
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[[Category: Rna-directed dna polymerase]]
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[[Category: Aspartyl protease]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 21 10:14:24 2010''
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Revision as of 17:34, 26 July 2012

Image:1hxb.png

Template:STRUCTURE 1hxb

Contents

HIV-1 proteinase complexed with RO 31-8959

About this Structure

1hxb is a 2 chain structure of Virus protease with sequence from Viruses. The June 2000 RCSB PDB Molecule of the Month feature on HIV-1 Protease by David S. Goodsell is 10.2210/rcsb_pdb/mom_2000_6. Full crystallographic information is available from OCA.

See Also

Reference

  • Krohn A, Redshaw S, Ritchie JC, Graves BJ, Hatada MH. Novel binding mode of highly potent HIV-proteinase inhibitors incorporating the (R)-hydroxyethylamine isostere. J Med Chem. 1991 Nov;34(11):3340-2. PMID:1956054
  • Roberts NA, Martin JA, Kinchington D, Broadhurst AV, Craig JC, Duncan IB, Galpin SA, Handa BK, Kay J, Krohn A, et al.. Rational design of peptide-based HIV proteinase inhibitors. Science. 1990 Apr 20;248(4953):358-61. PMID:2183354
  • Hong L, Zhang XC, Hartsuck JA, Tang J. Crystal structure of an in vivo HIV-1 protease mutant in complex with saquinavir: insights into the mechanisms of drug resistance. Protein Sci. 2000 Oct;9(10):1898-904. PMID:11106162

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