3l3m

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3l3m.jpg|left|200px]]
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The entry 3l3m is ON HOLD
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{{STRUCTURE_3l3m| PDB=3l3m | SCENE= }}
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Authors: Park, C.H.
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===PARP complexed with A927929===
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Description: PARP complexed with A927929
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:15:37 2010''
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{{ABSTRACT_PUBMED_20337371}}
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==About this Structure==
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3L3M is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L3M OCA].
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==Reference==
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<ref group="xtra">PMID:20337371</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Park, C H.]]
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[[Category: Acetylation]]
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[[Category: Adp-ribosylation]]
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[[Category: Dna damage]]
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[[Category: Dna repair]]
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[[Category: Dna-binding]]
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[[Category: Glycosyltransferase]]
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[[Category: Metal-binding]]
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[[Category: Nad]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Protein-inhibitor complex]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 23 08:49:54 2010''

Revision as of 04:44, 23 June 2010

Template:STRUCTURE 3l3m

PARP complexed with A927929

Template:ABSTRACT PUBMED 20337371

About this Structure

3L3M is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Penning TD, Zhu GD, Gong J, Thomas S, Gandhi VB, Liu X, Shi Y, Klinghofer V, Johnson EF, Park CH, Fry EH, Donawho CK, Frost DJ, Buchanan FG, Bukofzer GT, Rodriguez LE, Bontcheva-Diaz V, Bouska JJ, Osterling DJ, Olson AM, Marsh KC, Luo Y, Giranda VL. Optimization of phenyl-substituted benzimidazole carboxamide poly(ADP-ribose) polymerase inhibitors: identification of (S)-2-(2-fluoro-4-(pyrrolidin-2-yl)phenyl)-1H-benzimidazole-4-carboxamide (A-966492), a highly potent and efficacious inhibitor. J Med Chem. 2010 Apr 22;53(8):3142-53. PMID:20337371 doi:10.1021/jm901775y

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