3lc5

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(New page: '''Unreleased structure''' The entry 3lc5 is ON HOLD Authors: Wang, S., Beck, R. Description: Selective Benzothiophine Inhibitors of Factor IXa ''Page seeded by [http://oca.weizmann.a...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:3lc5.jpg|left|200px]]
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The entry 3lc5 is ON HOLD
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{{STRUCTURE_3lc5| PDB=3lc5 | SCENE= }}
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Authors: Wang, S., Beck, R.
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===Selective Benzothiophine Inhibitors of Factor IXa===
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Description: Selective Benzothiophine Inhibitors of Factor IXa
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:17:36 2010''
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{{ABSTRACT_PUBMED_20121197}}
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==Disease==
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Known disease associated with this structure: Hemophilia B OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300746 300746]]
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==About this Structure==
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3LC5 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LC5 OCA].
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==Reference==
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<ref group="xtra">PMID:20121197</ref><references group="xtra"/>
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[[Category: Coagulation factor IXa]]
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[[Category: Homo sapiens]]
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[[Category: Beck, R.]]
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[[Category: Wang, S.]]
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[[Category: Blood coagulation]]
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[[Category: Calcium]]
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[[Category: Cleavage on pair of basic residue]]
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[[Category: Disease mutation]]
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[[Category: Disulfide bond]]
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[[Category: Egf-like domain]]
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[[Category: Gamma-carboxyglutamic acid]]
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[[Category: Glycoprotein]]
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[[Category: Hemophilia]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Hydroxylation]]
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[[Category: Peptidase s1]]
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[[Category: Pharmaceutical]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Protease]]
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[[Category: Protein-inhibitor complex]]
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[[Category: Secreted]]
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[[Category: Serine protease]]
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[[Category: Sulfation]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 25 13:42:42 2010''

Revision as of 11:42, 25 February 2010

Image:3lc5.jpg

Template:STRUCTURE 3lc5

Contents

Selective Benzothiophine Inhibitors of Factor IXa

Template:ABSTRACT PUBMED 20121197

Disease

Known disease associated with this structure: Hemophilia B OMIM:[300746]

About this Structure

3LC5 is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wang S, Beck R, Burd A, Blench T, Marlin F, Ayele T, Buxton S, Dagostin C, Malic M, Joshi R, Barry J, Sajad M, Cheung C, Shaikh S, Chahwala S, Chander C, Baumgartner C, Holthoff HP, Murray E, Blackney M, Giddings A. Structure Based Drug Design: Development of Potent and Selective Factor IXa (FIXa) Inhibitors. J Med Chem. 2010 Feb 25;53(4):1473-82. PMID:20121197 doi:10.1021/jm901476x

Page seeded by OCA on Thu Feb 25 13:42:42 2010

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