3lea

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(New page: '''Unreleased structure''' The entry 3lea is ON HOLD until Paper Publication Authors: Orth, P. Description: Crystal structure of the catalytic domain of TACE with Isoindolinone-bipheny...)
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'''Unreleased structure'''
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[[Image:3lea.jpg|left|200px]]
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The entry 3lea is ON HOLD until Paper Publication
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{{STRUCTURE_3lea| PDB=3lea | SCENE= }}
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Authors: Orth, P.
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===Crystal structure of the catalytic domain of TACE with Isoindolinone-biphenyl-hydantoin inhibitor===
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Description: Crystal structure of the catalytic domain of TACE with Isoindolinone-biphenyl-hydantoin inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:18:27 2010''
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{{ABSTRACT_PUBMED_20663669}}
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==About this Structure==
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3LEA is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LEA OCA].
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==Reference==
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<ref group="xtra">PMID:20663669</ref><references group="xtra"/>
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[[Category: ADAM 17 endopeptidase]]
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[[Category: Homo sapiens]]
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[[Category: Orth, P.]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Membrane]]
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[[Category: Metal-binding]]
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[[Category: Metalloprotease]]
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[[Category: Notch signaling pathway]]
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[[Category: Phosphoprotein]]
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[[Category: Protease]]
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[[Category: Transmembrane]]
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[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 8 11:49:00 2010''

Revision as of 08:36, 8 December 2010

Image:3lea.jpg

Template:STRUCTURE 3lea

Crystal structure of the catalytic domain of TACE with Isoindolinone-biphenyl-hydantoin inhibitor

Template:ABSTRACT PUBMED 20663669

About this Structure

3LEA is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yu W, Tong L, Kim SH, Wong MK, Chen L, Yang DY, Shankar BB, Lavey BJ, Zhou G, Kosinski A, Rizvi R, Li D, Feltz RJ, Piwinski JJ, Rosner KE, Shih NY, Siddiqui MA, Guo Z, Orth P, Shah H, Sun J, Umland S, Lundell DJ, Niu X, Kozlowski JA. Biaryl substituted hydantoin compounds as TACE inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5286-9. Epub 2010 Jul 1. PMID:20663669 doi:10.1016/j.bmcl.2010.06.134

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