3kmc
From Proteopedia
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{{STRUCTURE_3kmc| PDB=3kmc | SCENE= }} | {{STRUCTURE_3kmc| PDB=3kmc | SCENE= }} | ||
===Crystal structure of catalytic domain of TACE with tartrate-based inhibitor=== | ===Crystal structure of catalytic domain of TACE with tartrate-based inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3kmc]] is a 2 chain structure of [[A Disintegrin And Metalloproteinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KMC OCA]. | |
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| + | ==See Also== | ||
| + | *[[A Disintegrin And Metalloproteinase|A Disintegrin And Metalloproteinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020022498</ref><references group="xtra"/> |
[[Category: ADAM 17 endopeptidase]] | [[Category: ADAM 17 endopeptidase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Orth, P.]] | [[Category: Orth, P.]] | ||
[[Category: A disintegrin and metalloproteinase domain 17]] | [[Category: A disintegrin and metalloproteinase domain 17]] | ||
| - | [[Category: Alternative splicing]] | ||
[[Category: Cleavage on pair of basic residue]] | [[Category: Cleavage on pair of basic residue]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
[[Category: Metal-binding]] | [[Category: Metal-binding]] | ||
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[[Category: Notch signaling pathway]] | [[Category: Notch signaling pathway]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Snake venom-like protease]] | [[Category: Snake venom-like protease]] | ||
[[Category: Tnf-alpha convertase]] | [[Category: Tnf-alpha convertase]] | ||
[[Category: Tnf-alpha-converting enzyme]] | [[Category: Tnf-alpha-converting enzyme]] | ||
| - | [[Category: Zinc]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:39:04 2010'' | ||
Revision as of 13:35, 26 July 2012
Contents |
Crystal structure of catalytic domain of TACE with tartrate-based inhibitor
Template:ABSTRACT PUBMED 20022498
About this Structure
3kmc is a 2 chain structure of A Disintegrin And Metalloproteinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Rosner KE, Guo Z, Orth P, Shipps GW Jr, Belanger DB, Chan TY, Curran PJ, Dai C, Deng Y, Girijavallabhan VM, Hong L, Lavey BJ, Lee JF, Li D, Liu Z, Popovici-Muller J, Ting PC, Vaccaro H, Wang L, Wang T, Yu W, Zhou G, Niu X, Sun J, Kozlowski JA, Lundell DJ, Madison V, McKittrick B, Piwinski JJ, Shih NY, Arshad Siddiqui M, Strickland CO. The discovery of novel tartrate-based TNF-alpha converting enzyme (TACE) inhibitors. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1189-93. Epub 2009 Dec 5. PMID:20022498 doi:10.1016/j.bmcl.2009.12.004
Categories: ADAM 17 endopeptidase | Homo sapiens | Orth, P. | A disintegrin and metalloproteinase domain 17 | Cleavage on pair of basic residue | Glycoprotein | Hydrolase | Membrane | Metal-binding | Metalloprotease | Notch signaling pathway | Phosphoprotein | Protease | Snake venom-like protease | Tnf-alpha convertase | Tnf-alpha-converting enzyme | Zymogen
